[Surgical management of pregnancy-associated acute Stanford type A aortic dissection: analysis of 5 cases]

Nan Fang Yi Ke Da Xue Xue Bao. 2017 Nov 20;37(11):1555-1558. doi: 10.3969/j.issn.1673-4254.2017.11.22.
[Article in Chinese]

Abstract

Objective: To explore the diagnosis and treatment of pregnancy-associated acute Stanford type A aortic dissection to improve the maternal and fetal outcomes.

Methods: We analyzed the perioperative data of 5 pregnant women with acute Stanford type A aortic dissection treated between June, 2009 and February, 2017.

Results: The median age of the women was 30 years (range, 22-34 years) with gestational weeks of 23-38 weeks upon diagnosis. All the 5 patients received surgical interventions. Three patients underwent caesarean delivery and hysterectomy, and the fetuses survived after the surgery; 2 patients chose to continue pregnancy following the surgery, among whom one died due to postoperative complications and the other underwent termination of pregnancy. During follow-up, the surviving patients showed no endoleak in the descending aorta stent and the distal dissection remained stable.

Conclusion: The maternal and fetal outcomes of pregnancy-associated acute Stanford type A aortic dissection can be improved by multidisciplinary cooperation and optimization of the surgical approaches according to the time of pregnancy, fetal development and conditions of the aortic lesions.

目的: 探讨妊娠合并急性Stanford A型主动脉夹层的诊治方法,以提高母婴救治成功率。

方法: 回顾性分析2009年6月~2017年2月广东省人民医院5例妊娠期患急性Stanford A型主动脉夹层孕妇围术期资料, 通过对孕周及夹层病变程度、全身影响程度分析手术方式和时机。

结果: 5例患者中位年龄30岁(22~34岁),发病时孕周23~38周;5例均接受手术治疗,3例同期行剖宫产+子宫切除,2例继续妊娠。术后1例死于并发症。剖宫产3例胎儿均存活,继续妊娠者,1例胎儿宫内死亡,1例引产。随访期间,降主动脉支架无内漏,夹层远端无扩大。

结论: 在基于挽救母亲和胎儿生命的前提下,急性Stanford A型主动脉夹层孕妇术前应多学科综合评估,根据妊娠时间、胎儿发育情况、主动脉病变程度决定手术方案。

MeSH terms

  • Adult
  • Aorta / pathology
  • Aorta / surgery*
  • Aortic Dissection / surgery*
  • Blood Vessel Prosthesis Implantation
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / surgery*
  • Retrospective Studies
  • Stents
  • Treatment Outcome
  • Young Adult

Grants and funding

广东省省级科技计划项目(2015A020214017);广东省医学科学技术研究基金项目(201611810048265)