RETRACTED: Association of prior HPV vaccination with reduced preterm birth: A population based study

Vaccine. 2018 Jan 2;36(1):134-140. doi: 10.1016/j.vaccine.2017.11.020. Epub 2017 Nov 27.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This paper is being retracted at the request of the authors. The authors report that there was an incorrect interpretation of the odds ratio meaning that instead of HPV vaccination potentially being protective, there may be an associated increased risk of preterm delivery. The authors believe that an increased risk of preterm delivery is unlikely and not consistent with the evidence to date. Further, the authors have not been able to access the original source data as per protocol to check the data validity. The authors wish to repeat the study to reassure themselves that there were no data processing or other errors in the databases in order to reach definitive conclusions. Lastly, it is of serious concern to the Editor-in-Chief that the Conflict of Interest statement was only added to the paper by the authors after acceptance and was not made visible to the editor or reviewers prior to acceptance. The authors state that there was no input to the methodology, implementation and results of this study by any commercial entity. The pharma distribution company CSL mentioned in the conflict of interest statement only knew about the study after publication.

Keywords: HPV; Pregnancy; Preterm birth; Vaccination.

Publication types

  • Observational Study
  • Retracted Publication

MeSH terms

  • Cohort Studies
  • Female
  • Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18 / administration & dosage
  • Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18 / adverse effects*
  • Humans
  • Infant, Newborn
  • Maternal Age
  • New Zealand / epidemiology
  • Odds Ratio
  • Papillomavirus Infections / complications
  • Papillomavirus Infections / epidemiology
  • Papillomavirus Infections / prevention & control
  • Population Surveillance*
  • Pregnancy
  • Premature Birth / epidemiology
  • Premature Birth / etiology*
  • Retrospective Studies
  • Stillbirth / epidemiology
  • Uterine Cervical Neoplasms / prevention & control
  • Vaccination / adverse effects*
  • Young Adult

Substances

  • Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18