Influence of comorbidities on CD4+/CD8+ proportion in HIV-positive patients in Blumenau, State of Santa Catarina: a retrospective study

Rev Soc Bras Med Trop. 2017 Sep-Oct;50(5):666-669. doi: 10.1590/0037-8682-0523-2016.

Abstract

Introduction: The objective was to identify comorbidities related to HIV-positive patients in Blumenau, State of Santa Catarina.

Methods: A retrospective, descriptive observational design study which analyzed data from 424 patients assisted by the sexually transmitted disease/acquired immunodeficiency syndrome (STD/AIDS) Specialized Care Service (SCS).

Results: Of 424 medical records analyzed, 388 patients presented CD4+/CD8+ ratios lower than 1. The most prevalent comorbidities were smoking, depression, alcoholism, and herpes zoster infection, in males and females.

Conclusions: The most relevant comorbidity in both genders was herpes zoster, an important marker of immunity in patients. The lowest mean was observed among patients with neurotoxoplasmosis.

Publication types

  • Observational Study

MeSH terms

  • Acquired Immunodeficiency Syndrome / blood*
  • Acquired Immunodeficiency Syndrome / epidemiology*
  • Adult
  • Alcoholism / blood
  • Alcoholism / epidemiology
  • Brazil / epidemiology
  • CD4-CD8 Ratio / statistics & numerical data*
  • Comorbidity
  • Depression / blood
  • Depression / epidemiology
  • Female
  • Herpes Zoster / blood
  • Herpes Zoster / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Reference Values
  • Retrospective Studies
  • Risk Factors
  • Sex Distribution
  • Smoking / blood
  • Smoking / epidemiology
  • Young Adult