[Ocular sarcoidosis : Diagnosis and therapy]

Ophthalmologe. 2017 Sep;114(9):865-876. doi: 10.1007/s00347-017-0552-5.
[Article in German]

Abstract

Sarcoidosis is a multisystem disorder of unknown cause. Ophthalmic involvement occurs in up to 60% of all patients, often as the first manifestation of sarcoidosis. Because of the heterogeneous clinical presentation diagnosis can be difficult; therefore the International Workshop on Ocular Sarcoidosis (IWOS 2009) diagnostic criteria based on clinical presentation, laboratory investigations and imaging techniques enable establishment of the diagnosis. Patients suffering from sarcoidosis should be treated by both ophthalmologists and internal physicians. Corticosteroids are commonly used for treatment, although in some patients the therapy has to be escalated by further immunosuppressants. Finally, a good cooperation between ophthalmologists and internal physicians results in a mostly good prognosis.

Keywords: Boeck’s disease; Corticosteroids; Granulomatous inflammation; Multisystem disease; Uveitis.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Eye Diseases / diagnosis*
  • Eye Diseases / drug therapy
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Interdisciplinary Communication
  • Intersectoral Collaboration
  • Magnetic Resonance Imaging
  • Prognosis
  • Sarcoidosis / diagnosis*
  • Sarcoidosis / drug therapy

Substances

  • Adrenal Cortex Hormones
  • Immunosuppressive Agents