The 11th C2H2 zinc finger and an adjacent C-terminal arm are responsible for TZAP recognition of telomeric DNA

Cell Res. 2018 Jan;28(1):130-134. doi: 10.1038/cr.2017.141. Epub 2017 Nov 14.

Authors

Yaqing Zhao¹, Guang Zhang¹, Chao He², Yide Mei¹, Yunyu Shi¹, Fudong Li¹

Affiliations

¹ Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230026, China.
² Anhui Key Laboratory of Modern Biomanufacturing and School of Life Sciences, Anhui University, Hefei, Anhui 230601, China.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

CYS2-HIS2 Zinc Fingers*
DNA* / chemistry
DNA* / metabolism
DNA-Binding Proteins* / chemistry
DNA-Binding Proteins* / metabolism
Humans
Telomere* / chemistry
Telomere* / metabolism
Transcription Factors* / chemistry
Transcription Factors* / metabolism

Substances

DNA-Binding Proteins
Transcription Factors
ZBTB48 protein, human
DNA