Glycated haemoglobin is increased in critically ill patients with stress hyperglycaemia: Implications for risk of diabetes in survivors of critical illness

Yang T Du; Palash Kar; Yasmine Ali Abdelhamid; Michael Horowitz; Adam M Deane

doi:10.1016/j.diabres.2017.10.029

Glycated haemoglobin is increased in critically ill patients with stress hyperglycaemia: Implications for risk of diabetes in survivors of critical illness

Diabetes Res Clin Pract. 2018 Jan:135:73-75. doi: 10.1016/j.diabres.2017.10.029. Epub 2017 Nov 11.

Authors

Yang T Du¹, Palash Kar², Yasmine Ali Abdelhamid², Michael Horowitz³, Adam M Deane⁴

Affiliations

¹ Discipline of Medicine, The University of Adelaide, Adelaide, SA 5000, Australia; Endocrine and Metabolic Unit, Royal Adelaide Hospital, Adelaide, SA 5000, Australia. Electronic address: yang.du@sa.gov.au.
² Discipline of Acute Care Medicine, The University of Adelaide, Adelaide, SA 5000, Australia; Intensive Care Unit, Royal Adelaide Hospital, Adelaide, SA 5000, Australia.
³ Discipline of Medicine, The University of Adelaide, Adelaide, SA 5000, Australia; Endocrine and Metabolic Unit, Royal Adelaide Hospital, Adelaide, SA 5000, Australia.
⁴ Intensive Care Unit, Royal Melbourne Hospital, Parkville, VIC 3050, Australia.

PMID: 29133202
DOI: 10.1016/j.diabres.2017.10.029

Abstract

It remains uncertain if stress hyperglycaemia (SH) indicates a long-term predisposition to the development of type 2 diabetes. We conducted a retrospective observational study in critically ill patients and found SH to be associated with an increased HbA1c, which may indicate an increased risk of type 2 diabetes.

Keywords: Diabetes; Haemoglobin A1c; Hyperglycaemia; Intensive care unit.

MeSH terms

Anxiety / complications*
Anxiety / pathology
Critical Illness / mortality*
Diabetes Mellitus, Type 2 / complications*
Diabetes Mellitus, Type 2 / mortality
Diabetes Mellitus, Type 2 / pathology
Female
Glycated Hemoglobin / analysis
Glycated Hemoglobin / metabolism*
Humans
Hyperglycemia / etiology*
Hyperglycemia / pathology
Male
Middle Aged
Retrospective Studies
Risk
Survivors

Substances

Glycated Hemoglobin A