Update in Chronic Lung Allograft Dysfunction

Rupal J Shah; Joshua M Diamond

doi:10.1016/j.ccm.2017.07.009

Update in Chronic Lung Allograft Dysfunction

Clin Chest Med. 2017 Dec;38(4):677-692. doi: 10.1016/j.ccm.2017.07.009. Epub 2017 Sep 21.

Authors

Rupal J Shah¹, Joshua M Diamond²

Affiliations

¹ Division of Pulmonary, Allergy and Critical Care Medicine, University of California, San Francisco, 350 Parnassus Avenue, Room 305, San Francisco, CA 94117, USA. Electronic address: rupal.shah@ucsf.edu.
² Division of Pulmonary, Allergy and Critical Care Medicine, University of Pennsylvania, 3400 Spruce Street, 821 West Gates, Philadelphia, PA 19010, USA.

PMID: 29128018
DOI: 10.1016/j.ccm.2017.07.009

Abstract

Chronic lung allograft dysfunction (CLAD) is the major limitation to posttransplant survival. This review highlights the evolving definition of CLAD, risk factors, treatment, and expected outcomes after the development of CLAD.

Keywords: Bronchiolitis obliterans syndrome; Chronic lung allograft dysfunction; Diagnosis; Risk factors; Treatment.

Publication types

Review

MeSH terms

Allografts / pathology*
Bronchiolitis Obliterans / etiology*
Bronchiolitis Obliterans / pathology
Chronic Disease
Humans
Lung Transplantation / adverse effects*
Lung Transplantation / methods
Risk Factors