Photodermatoses in the Pigmented Skin

Adv Exp Med Biol. 2017:996:111-122. doi: 10.1007/978-3-319-56017-5_10.

Abstract

Skin colour (specifically in relation to its melanin content and composition) has a marked influence on its interaction with ultraviolet light. Eumelanin has mainly photoprotective properties while pheomelanin has the ability to cause formation of reactive oxygen species. This difference is responsible for the difference in incidence and presentation of various idiopathic photodermatoses in dark skinned patients compared to those with lighter skin types. Certain conditions are peculiar to darker skins including pin point popular variant of polymorphous light eruption. These differences are discussed in this chapter while also highlighting the challenges faced in performing phototesting in patients with dark skin.

Keywords: Dark skin; Photodermatoses.

Publication types

  • Review

MeSH terms

  • Adult
  • Child
  • Female
  • Humans
  • Male
  • Melanins / metabolism*
  • Middle Aged
  • Oxidative Stress / radiation effects
  • Photosensitivity Disorders / diagnosis
  • Photosensitivity Disorders / etiology*
  • Photosensitivity Disorders / metabolism
  • Photosensitivity Disorders / physiopathology
  • Predictive Value of Tests
  • Prognosis
  • Reactive Oxygen Species / metabolism
  • Risk Factors
  • Skin / metabolism
  • Skin / pathology
  • Skin / radiation effects*
  • Skin Pigmentation / radiation effects*
  • Ultraviolet Rays / adverse effects*

Substances

  • Melanins
  • Reactive Oxygen Species
  • pheomelanin
  • eumelanin