'Basic and Applied Thermogenesis Research' Bridging the Gap

Stefania Carobbio; Anne-Claire Guénantin; Antonio Vidal-Puig

doi:10.1016/j.tem.2017.10.002

'Basic and Applied Thermogenesis Research' Bridging the Gap

Trends Endocrinol Metab. 2018 Jan;29(1):5-7. doi: 10.1016/j.tem.2017.10.002. Epub 2017 Oct 27.

Authors

Stefania Carobbio¹, Anne-Claire Guénantin², Antonio Vidal-Puig³

Affiliations

¹ Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK; Metabolic Research Laboratories, Addenbrooke's Treatment Centre, Institute of Metabolic Science, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK. Electronic address: sc22@sanger.ac.uk.
² Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK; Metabolic Research Laboratories, Addenbrooke's Treatment Centre, Institute of Metabolic Science, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
³ Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK; Metabolic Research Laboratories, Addenbrooke's Treatment Centre, Institute of Metabolic Science, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK. Electronic address: ajv22@cam.ac.uk.

PMID: 29110964
DOI: 10.1016/j.tem.2017.10.002

Abstract

Obesity is a major health problem without satisfactory pharmacological treatment. A promising strategy is to promote energy dissipation by activating brown/beige adipose tissue. However, for this strategy to succeed it requires improving the transferability amongst cellular, murine, and human systems and bridging the gap between basic and clinical research.

Keywords: brown adipose tissue; browning; energy expenditure; obesity; thermogenesis.

Publication types

Review

MeSH terms

Adipose Tissue, Brown / metabolism*
Animals
Biomedical Research*
Humans
Obesity / metabolism*
Thermogenesis / physiology*

Abstract

Publication types

MeSH terms

Grants and funding