A diagnostic approach to bone tumours

Pathology. 2017 Dec;49(7):675-687. doi: 10.1016/j.pathol.2017.08.003. Epub 2017 Oct 27.

Abstract

In this review we discuss an approach to diagnosing primary bone tumours, namely the cartilaginous, bone-forming, giant cell-rich, fibro-osseous and round cell neoplasms. Less common lesions including chordoma are also discussed. The value of integrating clinical, histopathological and relevant radiological features is emphasised with a view to providing the general histopathologist with a methodical approach to reaching an accurate diagnosis.

Keywords: Bone tumours; bone-forming tumours; cartilaginous tumours; diagnostic approach; fibro-osseous tumours; giant cell-rich tumours; notochord; round-cell tumours.

Publication types

  • Review

MeSH terms

  • Bone Neoplasms / classification
  • Bone Neoplasms / diagnostic imaging*
  • Bone Neoplasms / pathology
  • Diagnosis, Differential
  • Humans