Boronic acid-based chemical sensors for saccharides

Xiao-Tai Zhang; Guang-Jian Liu; Zhang-Wei Ning; Guo-Wen Xing

doi:10.1016/j.carres.2017.10.010

Boronic acid-based chemical sensors for saccharides

Carbohydr Res. 2017 Nov 27:452:129-148. doi: 10.1016/j.carres.2017.10.010. Epub 2017 Oct 20.

Authors

Xiao-Tai Zhang¹, Guang-Jian Liu², Zhang-Wei Ning², Guo-Wen Xing³

Affiliations

¹ College of Chemistry, Beijing Normal University, Beijing 100875, China; The Institute of Seawater Desalination and Multipurpose Utilization, State Oceanic Administration, Tianjin 300192, China.
² College of Chemistry, Beijing Normal University, Beijing 100875, China.
³ College of Chemistry, Beijing Normal University, Beijing 100875, China. Electronic address: gwxing@bnu.edu.cn.

PMID: 29096186
DOI: 10.1016/j.carres.2017.10.010

Abstract

During the past decades, the interaction between boronic acids-functionalized sensors and saccharides is of great interest in the frontier domain of the interdiscipline concerning both biology and chemistry. Various boronic acid-based sensing systems have been developed to detect saccharides and corresponding derivatives in vitro as well as in vivo, which embrace unimolecular sensors, two-component sensing ensembles, functional assemblies, and boronic acid-loaded nanomaterials or surfaces. New sensing strategies emerge in endlessly with excellent selectivity and sensitivity. In this review, several typical sensing systems were introduced and some promising examples were highlighted to enable the deep insight of saccharides sensing on the basis of boronic acids.

Keywords: Assembly; Boronic acids; Detection; Fluorescence; Saccharides.

MeSH terms

Biosensing Techniques / methods*
Boronic Acids / chemistry*
Carbohydrates / chemistry*
Nanostructures / chemistry*

Substances

Boronic Acids
Carbohydrates