Novel pyridine-based Pd(II)-complex for efficient Suzuki coupling of aryl halides under microwaves irradiation in water

Ismail I Althagafi; Mohamed R Shaaban; Aisha Y Al-Dawood; Ahmad M Farag

doi:10.1186/s13065-017-0320-2

Novel pyridine-based Pd(II)-complex for efficient Suzuki coupling of aryl halides under microwaves irradiation in water

Chem Cent J. 2017 Sep 18;11(1):88. doi: 10.1186/s13065-017-0320-2.

Authors

Ismail I Althagafi¹, Mohamed R Shaaban^{2

3}, Aisha Y Al-Dawood¹, Ahmad M Farag⁴

Affiliations

¹ Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah Almukaramah, Mecca, Saudi Arabia.
² Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah Almukaramah, Mecca, Saudi Arabia. mrgenidi@uqu.edu.sa.
³ Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt. mrgenidi@uqu.edu.sa.
⁴ Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt.

Abstract

Suzuki C-C cross-coupling of aryl halides with aryl boronic acids using new phosphene-free palladium complexes as precatalysts was investigated. A pyridine-based Pd(II)-complex was used in open air under thermal as well as microwave irradiation conditions using water as an eco-friendly green solvent.

Keywords: C–C cross-coupling; Microwave irradiation; Palladium precatalyst; Suzuki–Miyaura.