UK trends of allergic occupational skin disease attributed to fragrances 1996-2015

Contact Dermatitis. 2018 Jan;78(1):33-40. doi: 10.1111/cod.12902. Epub 2017 Oct 27.

Abstract

Background: Fragrances are well known to cause allergic contact dermatitis (ACD). Occupationally related cases occur, with certain groups being at higher risk.

Objective: To investigate the incidence of occupationally related cases of cutaneous fragrance allergy and to evaluate trends.

Method: Data on incident cases of occupational ACD caused by fragrances between 1996 and 2015 (inclusive) reported to the EPIDERM surveillance scheme were analysed.

Results: Of the cases reported to EPIDERM during the study period, 5.2% had ACD attributed to fragrances. The highest annual incidence rates were observed in women. Hairdressers, beauticians and people working in related occupations had a 47-fold higher incidence rate ratio than the reference category (the average of all other occupations combined). Trends analysis suggested a non-significant increase in fragrance allergy over the study period among all occupations, and beauty and food workers, and a slight decrease in healthcare workers.

Conclusions: Fragrance allergy is a significant problem in an occupational setting. Although there was no significant change in the incidence of fragrance-related allergic occupational contact dermatitis (OCD) during the 20-year study period, this does not mirror the trend in OCD, which is falling. Fragrance allergy continues to be a major contributor to OCD, and contributes to a greater proportion of cases.

Keywords: beauticians; epidemiology; food handlers; fragrance allergy; healthcare workers; occupation.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Barbering
  • Beauty Culture
  • Dermatitis, Allergic Contact / epidemiology*
  • Dermatitis, Allergic Contact / etiology
  • Dermatitis, Occupational / epidemiology*
  • Dermatitis, Occupational / etiology
  • Epidemiological Monitoring
  • Female
  • Food Handling
  • Health Care Sector
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Perfume / adverse effects*
  • United Kingdom / epidemiology
  • Young Adult

Substances

  • Perfume