Psychotropic in the environment: risperidone residues affect the behavior of fish larvae

Sci Rep. 2017 Oct 26;7(1):14121. doi: 10.1038/s41598-017-14575-7.

Abstract

The ability to avoid and escape from predators are clearly relevant behaviors from the ecological perspective and directly interfere with the survival of organisms. Detected in the aquatic environment, risperidone can alter the behavior of exposed species. Considering the risk of exposure in the early stages of life, we exposed zebrafish embryos to risperidone during the first 5 days of life. Risperidone caused hyperactivity in exposed larvae, which in an environmental context, the animals may be more vulnerable to predation due to greater visibility or less perception of risk areas.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Behavior, Animal / drug effects*
  • Dose-Response Relationship, Drug
  • Drug Residues / pharmacology*
  • Larva / drug effects*
  • Psychotropic Drugs / pharmacology*
  • Risperidone / pharmacology*
  • Water Pollutants, Chemical / pharmacology*
  • Zebrafish*

Substances

  • Psychotropic Drugs
  • Water Pollutants, Chemical
  • Risperidone