Special variant of histiocytosis

Koen D Quint; Arjen H Cleven; Maarten H Vermeer

doi:10.1136/bcr-2017-221538

Special variant of histiocytosis

BMJ Case Rep. 2017 Oct 25:2017:bcr2017221538. doi: 10.1136/bcr-2017-221538.

Authors

Koen D Quint¹, Arjen H Cleven², Maarten H Vermeer¹

Affiliations

¹ Department of Dermatology, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands.
² Department of Pathology, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands.

Abstract

Indeterminate cell histiocytosis is a rare variant of histiocytosis. The diagnosis is currently based on presence and absence of immunohistochemical markers. The current case described an indeterminate cell histiocytosis with ETV3-NCOA2 translocation.

Keywords: Dermatology; Genetics; Haematology (incl Blood Transfusion).

Publication types

Case Reports

MeSH terms

Aged
Diagnosis, Differential
Histiocytosis / genetics*
Histiocytosis / pathology*
Histiocytosis / radiotherapy
Humans
Male
Nuclear Receptor Coactivator 2 / genetics*
Proto-Oncogene Proteins c-ets / genetics
Rare Diseases
Translocation, Genetic
Treatment Outcome
Ultraviolet Therapy / methods*

Substances

ETV3 protein, human
NCOA2 protein, human
Nuclear Receptor Coactivator 2
Proto-Oncogene Proteins c-ets