Klebsiella pneumoniae shows increasing emergence of multidrug-resistant lineages, including strains resistant to all available antimicrobial drugs. We conducted whole-genome sequencing of 178 highly drug-resistant isolates from a tertiary hospital in Lahore, Pakistan. Phylogenetic analyses to place these isolates into global context demonstrate the expansion of multiple independent lineages, including K. quasipneumoniae.
Keywords: Australia; ESBL; Klebsiella; Klebsiella pneumonia; Pakistan; United Kingdom; antimicrobial resistance; bacteria; children; extended-spectrum β-lactamase; multidrug resistance; neonatal infection.