A flexible photonic crystal cavity, consisting of a III-V active layer embedded in a flexible medium, with a line-defect by removing three air holes for nanoscale structural deformation detection is proposed and optimized. The cavity can hold the photonic band-gap modes with the fundamental mode located at approximately 686 nm, overlapping with the photoluminescence spectrum of the InGaP/InGaAlP quantum wells. Results of finite-difference time-domain simulations indicate that the L3 cavity features an ultra-compact mode volume of 10-3 µm3 and high quality factor of 104 at a sub-micron footprint within the studied visible wavelength. Theoretical optical strain sensitivities of approximately 4.5 and 3 nm per ε (1% strain for both) for the x and y directions are predicted, respectively. When the cavity is under large bending curvatures, the Q factor rapidly decreases from 8000 to 2000.