Polycystic ovary syndrome (PCOS) is an endocrine disorder with reproductive dysfunction and abnormal metabolic syndrome. However, its etiology is unknown yet. Androgen hypersecretion is one of the main features of PCOS. It has been found that PCOS has various effects on the offspring in reproductive, metabolic and nervous systems, including:increasing secretion of gonadotropin-releasing hormone and luteinizing hormone, ovarian morphological changes and abnormal secretion of sex hormones, leading to disorders of lipid and glucose metabolism, and increasing the risks of depression and autism. However, there is still lack of direct evidence, and more studies should be conducted on the underlying mechanism in future.
多囊卵巢综合征（PCOS）是一种生殖功能障碍与代谢异常并存的内分泌紊乱综合征，病因不明。雄激素分泌过多是PCOS的主要特征之一。PCOS子代生殖系统、代谢系统、神经精神系统均有不同程度的远期改变。PCOS子代有促性腺激素释放激素和促性腺激素分泌增加、卵巢形态改变、性激素分泌异常的表现，脂肪和糖代谢紊乱现象，子代抑郁症及自闭症的风险增加，但是目前缺乏直接相关的证据，相关机制仍需进一步研究。