Glucose Variability After Bariatric Surgery: Is Prediction of Diabetes Remission Possible?

Obes Surg. 2017 Dec;27(12):3341-3343. doi: 10.1007/s11695-017-2960-7.

Abstract

We aimed to corroborate glycemic control after bariatric surgery (BS) using continuous glucose monitoring (CGM) and analyze if data could predict long-term outcome. We evaluated 24 of our patients with type 2 diabetes who underwent BS (12 Roux-en-Y gastric bypass, RYGB, and 12 single-anastomosis duodeno-ileal bypass with sleeve gastrectomy, SADI-S) and who were in remission after 18-24 months' follow-up. At this time, a CGM device was placed for 7 days. Patients were reevaluated thereafter for at least 5 years. Glucose variability (GV) was lower in patients after SADI-S and in the 18 patients who were still in remission after 5 years, and provided more information on long-term status than classical diabetes-related characteristics.

Keywords: Bariatric surgery; Diabetes mellitus; Diabetes remission; Glucose variability; Metabolic surgery; Obesity; Remission criteria; SADI-S; Type 2.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Bariatric Surgery* / rehabilitation
  • Blood Glucose / metabolism*
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / diagnosis*
  • Diabetes Mellitus, Type 2 / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Obesity, Morbid / blood
  • Obesity, Morbid / diagnosis
  • Obesity, Morbid / surgery
  • Postoperative Period
  • Prognosis
  • Remission Induction
  • Treatment Outcome

Substances

  • Blood Glucose