Peculiar purulence: Hypervirulent Klebsiella pneumoniae causing pyomyositis

Int J Infect Dis. 2017 Dec:65:90-92. doi: 10.1016/j.ijid.2017.09.030. Epub 2017 Oct 10.

Abstract

This report describes the first confirmed case of isolated pyomyositis caused by a hypervirulent strain of Klebsiella pneumoniae. Pyomyositis is almost universally caused by gram-positive organisms and while the recent emergence of invasive disease due to hypervirulent K. pneumoniae has been well documented, the most common clinical manifestation reported is liver abscess. The K. pneumoniae isolate in our case had a hypermucousviscous phenotype as demonstrated by a positive string test and was confirmed to be hypervirulent with molecular testing. Documenting the extrahepatic manifestations of hypervirulent Klebsiella pneumoniae strains is important to increase clinical awareness and in guiding empiric antibiotic regimens.

Keywords: Gastrocnemius; Klebsiella; Pyomyositis; Virulence.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Drug Resistance, Multiple, Bacterial
  • Humans
  • Klebsiella Infections / diagnosis*
  • Klebsiella Infections / drug therapy
  • Klebsiella pneumoniae / drug effects
  • Klebsiella pneumoniae / isolation & purification*
  • Levofloxacin / therapeutic use
  • Liver Abscess / diagnosis
  • Liver Abscess / microbiology
  • Male
  • Middle Aged
  • Penicillanic Acid / analogs & derivatives
  • Penicillanic Acid / therapeutic use
  • Phenotype
  • Piperacillin / therapeutic use
  • Piperacillin, Tazobactam Drug Combination
  • Pyomyositis / diagnosis*
  • Pyomyositis / drug therapy
  • Pyomyositis / microbiology
  • Vancomycin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Piperacillin, Tazobactam Drug Combination
  • Levofloxacin
  • Vancomycin
  • Penicillanic Acid
  • Piperacillin