Comparison of virtual monochromatic series, iodine overlay maps, and single energy CT equivalent images in head and neck cancer conspicuity

Clin Imaging. 2018 Mar-Apr:48:26-31. doi: 10.1016/j.clinimag.2017.09.015. Epub 2017 Sep 29.

Abstract

Objective: To compare lesion conspicuity amongst DECT monochromatic series (40, 45, 50keV), and single-energy CT (SECT) equivalent images in head and neck squamous cell carcinomas (HNSCC).

Methods: Two readers compared DECT images to 70keV SECT equivalent series in 39 patients with HNSCC on lesion margin, enhancement, and overall conspicuity.

Results: The 45keV and 50keV images were significantly better (p-values ≤0.001) than the SECT equivalent in lesion enhancement, margins, and overall conspicuity for both readers. Readers mostly preferred the 50keV monochromatic series.

Conclusion: DECT can provide better lesion visualization than SECT in HNSCC.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Carcinoma, Squamous Cell / diagnosis
  • Carcinoma, Squamous Cell / diagnostic imaging*
  • Carcinoma, Squamous Cell / pathology
  • Contrast Media
  • Female
  • Head and Neck Neoplasms / diagnosis
  • Head and Neck Neoplasms / diagnostic imaging*
  • Head and Neck Neoplasms / pathology
  • Humans
  • Iodides
  • Iodine
  • Male
  • Middle Aged
  • Sensitivity and Specificity
  • Squamous Cell Carcinoma of Head and Neck
  • Tomography, X-Ray Computed / methods*

Substances

  • Contrast Media
  • Iodides
  • Iodine