Optimizing the Nutritional Support of Adult Patients in the Setting of Cirrhosis

Nutrients. 2017 Oct 13;9(10):1114. doi: 10.3390/nu9101114.

Abstract

Aim: The aim of this work is to develop a pragmatic approach in the assessment and management strategies of patients with cirrhosis in order to optimize the outcomes in this patient population.

Method: A systematic review of literature was conducted through 8 July 2017 on the PubMed Database looking for key terms, such as malnutrition, nutrition, assessment, treatment, and cirrhosis. Articles and studies looking at associations between nutrition and cirrhosis were reviewed.

Results: An assessment of malnutrition should be conducted in two stages: the first, to identify patients at risk for malnutrition based on the severity of liver disease, and the second, to perform a complete multidisciplinary nutritional evaluation of these patients. Optimal management of malnutrition should focus on meeting recommended daily goals for caloric intake and inclusion of various nutrients in the diet. The nutritional goals should be pursued by encouraging and increasing oral intake or using other measures, such as oral supplementation, enteral nutrition, or parenteral nutrition.

Conclusions: Although these strategies to improve nutritional support have been well established, current literature on the topic is limited in scope. Further research should be implemented to test if this enhanced approach is effective.

Keywords: Child-Turcotte-Pugh; cirrhosis; dietary intervention; end-stage liver disease; improved oral intake; malnutrition; nutrition.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • End Stage Liver Disease / diagnosis
  • End Stage Liver Disease / epidemiology
  • End Stage Liver Disease / physiopathology
  • End Stage Liver Disease / therapy*
  • Humans
  • Liver Cirrhosis / diagnosis
  • Liver Cirrhosis / epidemiology
  • Liver Cirrhosis / physiopathology
  • Liver Cirrhosis / therapy*
  • Malnutrition / diagnosis
  • Malnutrition / epidemiology
  • Malnutrition / physiopathology
  • Malnutrition / therapy*
  • Nutrition Assessment
  • Nutritional Status*
  • Nutritional Support / methods*
  • Risk Factors
  • Treatment Outcome