Introduction: The study aimed to compare Bispectral Index (BIS) and non-BIS anesthetic protocols on postoperative recovery outcomes.
Evidence acquisition: Medline, PubMed, Cochrane, EMBASE, and Google Scholar databases were searched until January 21, 2016.
Evidence synthesis: Twenty-six studies were included with a total of 9537 patients. BIS monitoring was significantly associated with shorter time to eye opening (P=0.001), time to extubation (P<0.001), and time to orientation (P=0.002) compared with non-BIS monitoring. No difference between groups was seen with respect to hypoxemia, postoperative nausea and vomiting (PONV), time to oral fluid intake, and length of Postanesthesia Care Unit (PACU) stay (P values ≥0.185).
Conclusions: The use of BIS-monitoring is superior to non-BIS monitored anesthesia in terms of shorter time to eye-opening, extubation, and orientation. BIS monitor may be considered a safe and effective method for monitoring depth of anesthesia during surgery.