Characterization and application of azo dye (E)-N-phenyl-4-(thiazole-2-yldiazenyl)aniline (PDA) for biomedical sterilization

J Mech Behav Biomed Mater. 2018 Jan:77:408-413. doi: 10.1016/j.jmbbm.2017.09.033. Epub 2017 Sep 27.

Abstract

Sterilization is the certain and absolute decontamination of microorganisms totally from all manner of alive and active species. Sterilization devices used in the sterilization processes are between laboratory and external patient application devices of biomedical device technology, and they are designed to remove equipments from germs. The application potential of hetarilazo indole based azo dyes in the biomedical sterilization are known and azo dyes come into prominence in this class because of simplicity of their synthesis and procurement of low-cost raw materials. In this work, the application potential of a novel synthesized azo dye, (E)-N-phenyl-4-(thiazole-2-yldiazenyl)aniline was investigated as an indicator in the biomedical sterilization performing the electrochemical and spectroscopic characterizations. The application of indicator was tested by ethylene oxide, hydrogen peroxide and peracetic acid sterilization techniques introducing into various sterilization rolls.

Keywords: Azo dyes; Biomedical; Electrochemical; Pencil graphite electrode; Sterilization.

MeSH terms

  • Aniline Compounds / chemistry*
  • Azo Compounds / chemistry*
  • Colorimetry
  • Electrochemistry
  • Electrodes
  • Ethylene Oxide / chemistry
  • Hydrazones / chemistry
  • Hydrogen Peroxide / chemistry
  • Hydrogen-Ion Concentration
  • Indoles / chemistry*
  • Limit of Detection
  • Oxygen / chemistry
  • Peracetic Acid / chemistry
  • Spectrophotometry
  • Spectrophotometry, Ultraviolet
  • Sterilization / methods*
  • Surface Properties
  • Temperature
  • Thiazoles / chemistry*
  • Ultraviolet Rays

Substances

  • Aniline Compounds
  • Azo Compounds
  • Hydrazones
  • Indoles
  • Thiazoles
  • Hydrogen Peroxide
  • Peracetic Acid
  • Ethylene Oxide
  • Oxygen