Hematopoietic Stem Cell Transplantation in ADA2 Deficiency: Early Restoration of ADA2 Enzyme Activity and Disease Relapse upon Drop of Donor Chimerism

J Clin Immunol. 2017 Nov;37(8):746-750. doi: 10.1007/s10875-017-0449-8. Epub 2017 Oct 10.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Deaminase / genetics*
  • Autoimmunity / genetics
  • Child, Preschool
  • Chimerism
  • Disease Progression
  • Enzyme Activation
  • Female
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Immunologic Deficiency Syndromes / therapy*
  • Infant
  • Intercellular Signaling Peptides and Proteins / genetics*
  • Male
  • Recurrence
  • Tissue Donors

Substances

  • Intercellular Signaling Peptides and Proteins
  • ADA2 protein, human
  • Adenosine Deaminase