Meconium ileus in Cystic Fibrosis

Meghana Sathe; Roderick Houwen

doi:10.1016/j.jcf.2017.06.007

Meconium ileus in Cystic Fibrosis

J Cyst Fibros. 2017 Nov:16 Suppl 2:S32-S39. doi: 10.1016/j.jcf.2017.06.007.

Authors

Meghana Sathe¹, Roderick Houwen²

Affiliations

¹ UT Southwestern Medical Center, Dallas, TX,United States. Electronic address: meghana.sathe@childrens.com.
² University Medical Centre of Utrecht, Netherlands.

PMID: 28986020
DOI: 10.1016/j.jcf.2017.06.007

Abstract

Meconium ileus (MI) is often the first manifestation of cystic fibrosis (CF) and occurs in approximately 20% of patients diagnosed with CF. This article reviews the pathophysiology of MI and its clinical presentation. It focuses on the medical and surgical management emphasizing the importance of nutrition and a multidisciplinary approach to improve both short-term and long-term outcomes for CF patients with MI.

Keywords: Cystic fibrosis; Gastrografin; Meconium ileus; Meconium peritonitis.

Publication types

Review

MeSH terms

Cystic Fibrosis / complications*
Humans
Infant, Newborn
Meconium Ileus* / diagnosis
Meconium Ileus* / etiology
Meconium Ileus* / physiopathology
Meconium Ileus* / therapy
Patient Care Management / methods*