The LUNGe to Model Alveolar Lung Diseases in a Dish

Zheng Wang; Nan Tang

doi:10.1016/j.stem.2017.09.009

The LUNGe to Model Alveolar Lung Diseases in a Dish

Cell Stem Cell. 2017 Oct 5;21(4):413-414. doi: 10.1016/j.stem.2017.09.009.

Authors

Zheng Wang¹, Nan Tang²

Affiliations

¹ Graduate School of Peking Union Medical College, Beijing, 100730, China; National Institute of Biological Sciences, Beijing, 102206, China.
² National Institute of Biological Sciences, Beijing, 102206, China. Electronic address: tangnan@nibs.ac.cn.

PMID: 28985518
DOI: 10.1016/j.stem.2017.09.009

Abstract

Obtaining alveolar epithelial type 2 cells (AEC2s) from human pluripotent stem cells (hPSCs) offers great scientific and clinical promise. In this issue of Cell Stem Cell, Jacob et al. (2017) report a method for the directed differentiation of hPSCs into mature AEC2s and demonstrate its application in modeling alveolar lung diseases.

Publication types

Comment

MeSH terms

Alveolar Epithelial Cells / cytology
Cell Differentiation
Humans
Lung / cytology
Lung Diseases*
Pluripotent Stem Cells / cytology*