Catalytically inactive Gla-domainless factor Xa binds to TFPI and restores ex vivo coagulation in hemophilia plasma

Haematologica. 2017 Dec;102(12):e483-e485. doi: 10.3324/haematol.2017.174037. Epub 2017 Oct 5.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocatalysis
  • Blood Coagulation*
  • Factor Xa / metabolism*
  • Hemophilia A / blood*
  • Humans
  • Lipoproteins / metabolism*
  • Models, Molecular
  • Plasma
  • Protein Binding

Substances

  • Lipoproteins
  • lipoprotein-associated coagulation inhibitor
  • Factor Xa