A theoretical model for Zika virus transmission

PLoS One. 2017 Oct 4;12(10):e0185540. doi: 10.1371/journal.pone.0185540. eCollection 2017.

Abstract

In this paper, we present and analyze an SEIR Zika epidemic model. Firstly, we investigate the model with constant controls. The steady states of the model is found to be locally and globally asymptotically stable. Thereafter, we incorporate time dependent controls into the model in order to investigate the optimal effects of bednets, treatments of infective and spray of insecticides on the disease spread. Furthermore, we used Pontryagin's Maximum Principle to determine the necessary conditions for effective control of the disease. Also, the numerical results were presented.

MeSH terms

  • Humans
  • Insecticides / administration & dosage
  • Models, Theoretical*
  • Mosquito Vectors / virology
  • Zika Virus Infection / epidemiology
  • Zika Virus Infection / prevention & control
  • Zika Virus Infection / transmission*

Substances

  • Insecticides

Grants and funding

The author(s) received no specific funding for this work.