Technical Note: Dosimetric characteristics of the ocular beam line and commissioning data for an ocular proton therapy planning system at the Proton Therapy Center Houston

Med Phys. 2017 Dec;44(12):6661-6671. doi: 10.1002/mp.12605. Epub 2017 Oct 26.

Abstract

Purpose: To systematically analyze and present the properties of a small-field, double-scattering proton beam line intended to be used for the treatment of ocular cancer, and to provide configuration data for commission of the Eclipse Ocular Proton Planning System.

Methods: Measurements were made using ionization chambers, diodes, and films to determine dose profiles and output factors of the proton beams of the beam line at the Proton Therapy Center Houston. In parallel, Monte Carlo simulations were performed to validate the measured data and to provide additional insight into detailed beam parameters that are hard to measure, such as field size factors and a comparison of output factors as a function of circular and rectangular fields.

Results: The presented data comprise depth dose profiles, including distal and proximal profiles used to configure the Eclipse Ocular Proton Planning system, distal fall-off widths, lateral profiles and penumbrae sizes, as well as output factors as a function of field size, SOBP width, range shifter thickness, snout position, and source-to-surface distance.

Conclusions: We have completed a comprehensive characterization of the beam line. The data will be useful to characterize proton beams in clinical and experimental small-field applications.

Keywords: ocular proton beam line; proton therapy; small proton field properties.

MeSH terms

  • Eye / radiation effects*
  • Monte Carlo Method
  • Proton Therapy*
  • Radiotherapy Planning, Computer-Assisted / methods*