Incidental late diagnosis of cystic fibrosis following AH1N1 influenza virus pneumonia: a case report

J Med Case Rep. 2017 Oct 1;11(1):278. doi: 10.1186/s13256-017-1430-0.

Abstract

Background: Cystic fibrosis is an autosomal recessive disorder characterized by chronic progressive multisystem involvement. AH1N1 virus infections caused classic influenza symptoms in the majority of cystic fibrosis patients while others experienced severe outcomes.

Case presentation: We report a case of late incidental cystic fibrosis diagnosis in a young Caucasian man suffering from respiratory failure following infection due to AH1N1 influenza virus. The patient was admitted to our department with fever, cough, and dyspnea at rest unresponsive to antibiotics CONCLUSIONS: Late diagnosis of cystic fibrosis in uncommon. This report highlights the importance of early cystic fibrosis diagnosis to minimize risk of occurrence of potential life-threatening complications.

Keywords: Cystic fibrosis; Pneumonia; Respiratory failure.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Ceftazidime / administration & dosage
  • Colistin / administration & dosage
  • Cystic Fibrosis / complications*
  • Cystic Fibrosis / diagnosis*
  • Cystic Fibrosis / rehabilitation
  • Cystic Fibrosis / therapy
  • Delayed Diagnosis*
  • Drainage, Postural
  • Genetic Testing
  • Humans
  • Incidental Findings
  • Influenza A Virus, H1N1 Subtype* / isolation & purification
  • Influenza, Human / complications*
  • Influenza, Human / drug therapy
  • Influenza, Human / virology*
  • Male
  • Meropenem
  • Pneumonia / complications*
  • Pneumonia / diagnostic imaging
  • Pneumonia / drug therapy
  • Pneumonia / virology
  • Referral and Consultation
  • Sweat
  • Thienamycins / administration & dosage
  • Tomography, X-Ray Computed
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Thienamycins
  • Ceftazidime
  • Meropenem
  • Colistin