Background: Recently, with improvements in computed tomography angiography and digital subtraction angiography, the assessment of certain morphologic traits of anterior communicating artery aneurysms (ACoAA) has drawn great attention. The determination of specific factors associated with rupture would provide much-needed guidance for the treatment of unruptured intracranial aneurysms, such as surgical clipping or endovascular coiling. Morphologic factors include, but are not limited to, aneurysm size, number, shape, dome direction, neck/dome ratio, and relationship of the aneurysm to the surrounding vessels. However, the results of previous investigations concerning morphologic parameters have yielded inconsistent results.
Methods: This review presents and analyzes the literature on the morphology of ACoAAs and risk of rupture.
Results: This literature review reveals that the strongest predictors of ACoAA rupture are size ratio, direction of the dome, and fenestration. These were the only factors that were either unanimously or near unanimously found to be predictive of rupture across multiple studies.
Conclusions: The size ratio, direction of the dome, and fenestration should be examined most meticulously when deciding when to treat an ACoAA.
Keywords: Anterior communicating artery; Intracranial aneurysm; Morphology; Rupture.
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