Background: Eating disorder is culture related, and the clinical symptoms are different between eastern and western patients. So the validity of feeding and eating disorders in the upcoming ICD-11 guide for Chinese patients is unclear.
Aims: To explore the latent class structure of Chinese patients with eating disorder and the cross-cultural validity of the eating disorder section of the new ICD-11 guide in China.
Methods: A total of 379 patients with eating disorders at Shanghai Mental Health Center were evaluated using the EDI questionnaire and a questionnaire developed by researchers from 2010 to 2016. SPSS 20.0 was used to enter data and analyze demographic data, and Latent GOLD was employed to conduct latent profile analysis.
Results: According to the results of latent profile analysis, patients with eating disorder were divided into five classes: low-weight fasting class (23.1%), non-fat-phobic binge/purge class (21.54%), low-fat-phobic binge class (19.27%), fat-phobic binge class (19.27%), and non-fat-phobic low-weight class (16.76%). Among the clinical symptoms extracted, there were significant differences in Body Mass Index (BMI), binge eating behavior, self-induced vomiting, laxative use and fat-phobic opinion; while there was no significant difference in restrictive food intake.
Conclusions: Based on the clinical symptoms, there are five latent classes in Chinese patients with eating disorder, which is in accordance with the diagnostic categories of feeding and eating disorder in ICD-11. However, further work is needed in improving the fat-phobic opinion of patients with eating disorder and clarifying the BMI standard of thinness in the Chinese population.
背景: 进食障碍是一种文化相关疾病，东西方患者的 临床表现有所不同，新版ICD-11 指南即将出版，其喂 养和进食障碍部分在中国进食障碍患者中的适用性尚 不明确。.
目的: 探索中国进食障碍患者的潜在类别结构，研究 新版ICD-11 指南中进食障碍相关部分在中国的跨文化 适用性。.
方法: 采用自制问卷和进食障碍问卷量表对379 名 2010-2016 年于上海市精神卫生中心就诊的进食障碍患 者的症状进行评估，使用SPSS20.0 录入数据、处理人 口学资料，通过Latent GOLD 4.5 进行潜在剖面分析。.
结果: 依据潜在剖面分析结果可以将进食障碍分成: 极低体重限制进食组（23.17%），无怕胖暴食清除组 （21.54%），低水平怕胖暴食组（19.27%），怕胖暴 食组（19.27%），极低体重无怕胖组（16.76%）。在 提取的临床症状表现中，BMI、有无暴食行为、有无催吐、 有无服用导泻剂及怕胖观念存在显著性差异，而有无 限制性进食并无显著性差异。.
结论: 中国的进食障碍患者根据症状可以分成五个潜 类别，基本符合ICD-11 喂养和进食障碍的诊断分类。 但进食障碍患者的怕胖观念标准和中国人群的低体重 标准有待进一步完善。.
Keywords: ICD-11; anorexia nervosa; eating disorders; latent class modeling.