Agreed Definitions and a Shared Vision for New Standards in Stroke Recovery Research: The Stroke Recovery and Rehabilitation Roundtable Taskforce

Julie Bernhardt; Kathryn S Hayward; Gert Kwakkel; Nick S Ward; Steven L Wolf; Karen Borschmann; John W Krakauer; Lara A Boyd; S Thomas Carmichael; Dale Corbett; Steven C Cramer

doi:10.1177/1545968317732668

Agreed Definitions and a Shared Vision for New Standards in Stroke Recovery Research: The Stroke Recovery and Rehabilitation Roundtable Taskforce

Neurorehabil Neural Repair. 2017 Sep;31(9):793-799. doi: 10.1177/1545968317732668.

Authors

Julie Bernhardt^{1

2}, Kathryn S Hayward^{1

2

3}, Gert Kwakkel^{4

5}, Nick S Ward^{6

7}, Steven L Wolf^{8

9}, Karen Borschmann^{1

2}, John W Krakauer¹⁰, Lara A Boyd^{3

11}, S Thomas Carmichael¹², Dale Corbett^{13

14}, Steven C Cramer¹⁵

Affiliations

¹ 1 Stroke Division, The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Australia.
² 2 NHMRC Centre of Research Excellence Stroke Rehabilitation and Brain Recovery, Melbourne, Australia.
³ 3 Department of Physical Therapy, University of British Columbia, Vancouver, Canada.
⁴ 4 Department Rehabilitation Medicine, MOVE Research Institute, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam, the Netherlands.
⁵ 5 Department of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University Chicago, Evanston, IL, USA.
⁶ 6 Sobell Department of Motor Neuroscience, UCL Institute of Neurology, Queen Square, London, UK.
⁷ 7 The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
⁸ 8 Department of Rehabilitation Medicine, Department of Medicine, and Department of Cell Biology, Division of Physical Therapy, Emory University School of Medicine, Atlanta, GA, USA.
⁹ 9 Atlanta VA Center for Visual and Neurocognitive Rehabilitation, Atlanta, GA, USA.
¹⁰ 10 Departments of Neurology, Neuroscience, and Physical Medicine & Rehabilitation, Johns Hopkins University, Baltimore, MD, USA.
¹¹ 11 The Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver Canada.
¹² 12 Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
¹³ 13 Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Canada.
¹⁴ 14 Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, Ottawa, Canada.
¹⁵ 15 Departments of Neurology, Anatomy & Neurobiology, and Physical Medicine & Rehabilitation, University of California, Irvine, CA, USA.

PMID: 28934920
DOI: 10.1177/1545968317732668

Abstract

The first Stroke Recovery and Rehabilitation Roundtable established a game changing set of new standards for stroke recovery research. Common language and definitions were required to develop an agreed framework spanning the four working groups: translation of basic science, biomarkers of stroke recovery, measurement in clinical trials and intervention development and reporting. This paper outlines the working definitions established by our group and an agreed vision for accelerating progress in stroke recovery research.

Keywords: Stroke; definitions; rehabilitation; research standards; stroke recovery; translation.

MeSH terms

Animals
Clinical Trials as Topic
Humans
Recovery of Function / physiology*
Stroke / complications*
Stroke Rehabilitation / methods*
Translational Research, Biomedical* / methods
Translational Research, Biomedical* / standards