Caring about Power Analyses

ACS Chem Neurosci. 2017 Nov 15;8(11):2352-2354. doi: 10.1021/acschemneuro.7b00341. Epub 2017 Sep 21.

Abstract

Everyone should care deeply about statistical power and effect size given that the current estimates of wasted nonreproducible and exaggerated research findings range from 50 to 85%, combined with the mandates from the National Institutes of Health (NIH) that proposal reviewers focus on scientific rigor and investigators consider sex as a biological variable. In this Viewpoint, we provide recommendations and resources regarding power analyses aimed at enhancing rigor, and hence decreasing waste, when designing experiments. As part of this effort, we also make recommendations for reporting key statistics that will aid others in estimating sample size based on published research.

Keywords: Data analyses; effect size; replication crisis; scientific rigor.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Biostatistics* / methods
  • Consultants
  • Data Interpretation, Statistical*
  • Editorial Policies
  • Humans
  • National Institutes of Health (U.S.)
  • Periodicals as Topic / standards
  • Research / standards
  • Research Design / standards
  • United States