[Research progress of Guanxin Danshen formula and its effective components in treating coronary artery heart disease]

Zhongguo Zhong Yao Za Zhi. 2016 Oct;41(20):3721-3726. doi: 10.4268/cjcmm20162004.
[Article in Chinese]

Abstract

Coronary artery heart disease (CHD) is one of the common cardiovascular diseases in clinical. The morbidity and mortality of CHD recently continue increasing in our country, which has aroused wide attention. Many studies confirm that traditional Chinese medicine has better therapeutic effect on CHD. Guanxin Danshen formula, widely used in the treatment of CHD, consists of Salviae Miltiorrhizae Radix et Rhizoma, Notoginseng Radix et Rhizoma and volatile oil from Dalbergiae Odoriferae Lignum, and has the efficacy in promoting blood circulation to resolve stasis, regulating the circulation of Qi and alleviating pain. This review summarized the pharmacologic effects and mechanism of Guanxin Danshen formula and its effective components in the treatment of CHD to provide reference for its fundamental research and clinical application.

Keywords: Guanxin Danshen formula; coronary artery heart disease; mechanism; pharmacological effects.

Publication types

  • Review

MeSH terms

  • Coronary Vessels / physiopathology
  • Drugs, Chinese Herbal / pharmacology*
  • Heart Diseases / drug therapy*
  • Humans
  • Medicine, Chinese Traditional
  • Rhizome
  • Salvia miltiorrhiza

Substances

  • Drugs, Chinese Herbal