Ultra-high pressure modified cellulosic fibres with antimicrobial properties

Ana M Salgueiro; Mauro D Santos; Jorge A Saraiva; Filipe Almeida; Isabel Sousa; João Tedim; Helena I S Nogueira; Dmitry V Evtuguin

doi:10.1016/j.carbpol.2017.07.081

Ultra-high pressure modified cellulosic fibres with antimicrobial properties

Carbohydr Polym. 2017 Nov 1:175:303-310. doi: 10.1016/j.carbpol.2017.07.081. Epub 2017 Jul 31.

Authors

Ana M Salgueiro¹, Mauro D Santos², Jorge A Saraiva², Filipe Almeida³, Isabel Sousa⁴, João Tedim⁴, Helena I S Nogueira⁵, Dmitry V Evtuguin⁶

Affiliations

¹ CICECO - Aveiro Institute of Materials, Chemistry Department, University of Aveiro, Campus de Santiago, 3810-193, Aveiro, Portugal; QOPNA, Chemistry Department, University of Aveiro, Campus de Santiago, 3810-193, Aveiro, Portugal.
² QOPNA, Chemistry Department, University of Aveiro, Campus de Santiago, 3810-193, Aveiro, Portugal.
³ Renova FPA S.A., 2354, Torres Novas, Portugal.
⁴ CICECO - Aveiro Institute of Materials, Department of Materials and Ceramic Engineering, University of Aveiro, 3810-193, Aveiro, Portugal.
⁵ CICECO - Aveiro Institute of Materials, Chemistry Department, University of Aveiro, Campus de Santiago, 3810-193, Aveiro, Portugal.
⁶ CICECO - Aveiro Institute of Materials, Chemistry Department, University of Aveiro, Campus de Santiago, 3810-193, Aveiro, Portugal; Department of Wood Chemistry, St. Petersburg Forest Technical University, Institutsky per. 5, 194021, St. Petersburg, Russian Federation. Electronic address: Dmitrye@ua.pt.

PMID: 28917870
DOI: 10.1016/j.carbpol.2017.07.081

Abstract

In this work bleached E. globulus kraft pulp was doped with polyhexamethylene biguanide (PHMB) from an aqueous solution or from a suspension of silica capsules (PHMB@silica) by impregnation under atmospheric or ultra-high pressure (UHP) conditions (500MPa). The antimicrobial properties of pulps were evaluated towards gram-negative E. coli and gram-positive L. innocua bacteria. PHMB loads below 500mg per kg of pulp revealed negligible bacteriostatic properties, whereas PHMB loads of ca 3000-4000mg per kg demonstrated bactericidal properties of pulp without significant deterioration of its mechanical strength. The UHP impregnation allowed significant improvement of PHMB uptake. Thus, under equal conditions, PHMB uptake was ca 25% greater under UHP than under atmospheric pressure impregnation, whereas the leachable amounts of PHMB in both pulps were comparable. The sorption of PHMB@silica on pulp in suspension under UHP conditions was ca 17% greater than under atmospheric pressure with almost 70% increase of leachable PHMB.

Keywords: Antimicrobial activity; Cellulosic fibres; High-pressure treatment; PHMB.

MeSH terms

Anti-Bacterial Agents / chemistry*
Biguanides / chemistry*
Carbohydrates
Cellulose / chemistry*
Escherichia coli
Gram-Positive Bacteria
Pressure

Substances

Anti-Bacterial Agents
Biguanides
Carbohydrates
Cellulose