Magnetic Resonance Thermometry and Laser Interstitial Thermal Therapy for Brain Tumors

Danilo Silva; Mayur Sharma; Rupa Juthani; Antonio Meola; Gene H Barnett

doi:10.1016/j.nec.2017.05.015

Magnetic Resonance Thermometry and Laser Interstitial Thermal Therapy for Brain Tumors

Neurosurg Clin N Am. 2017 Oct;28(4):525-533. doi: 10.1016/j.nec.2017.05.015. Epub 2017 Jul 4.

Authors

Danilo Silva¹, Mayur Sharma¹, Rupa Juthani¹, Antonio Meola¹, Gene H Barnett²

Affiliations

¹ Rose Ella Burkhardt Brain Tumor and Neuro-oncology Center, Department of Neurosurgery, Neurological Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
² Rose Ella Burkhardt Brain Tumor and Neuro-oncology Center, Department of Neurosurgery, Neurological Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA. Electronic address: barnetg@ccf.org.

PMID: 28917281
DOI: 10.1016/j.nec.2017.05.015

Abstract

Recent technological advancements in intraoperative imaging are shaping the way for a new era in brain tumor surgery. Magnetic resonance thermometry has provided intraoperative real-time imaging feedback for safe and effective application of laser interstitial thermal therapy (LITT) in neuro-oncology. Thermal ablation has also established itself as a surgical option in epilepsy surgery and is currently used in spine oncology with promising results. This article reviews the principles and rationale as well as the clinical application of LITT for brain tumors. It also discusses the technical nuances of the current commercially available systems.

Keywords: Brain tumors; Intraoperative imaging; Laser interstitial thermal therapy; Thermometry.

Publication types

Review

MeSH terms

Brain Neoplasms / therapy*
Epilepsy / therapy
Humans
Hyperthermia, Induced / methods*
Laser Therapy / methods*
Magnetic Resonance Imaging, Interventional / methods*