[Mechanism of anti-aging therapy on Parkinson's disease]

Zhongguo Zhong Yao Za Zhi. 2016 Jul;41(14):2680-2686. doi: 10.4268/cjcmm20161419.
[Article in Chinese]

Abstract

Many studies have shown that anti-aging treatment has value to prevention and treatment of some diseases. For the treatment of Parkinson' s disease, clinical and experimental researches have proved the potential value of anti-aging treatment, yet the mechanism remains unclear. For this reason, this work used the anti-aging prescriptions of Buyang Huanwu decoction in traditional Chinese medicines example to discover the anti-aging treatment mechanism on Parkinson's disease. The results showed that the mechanism of mitochondrial damage, apoptosis, free radicals and oxidative stress could contribute to the treatment of Parkinson' s disease. Buyang Huanwu decoction is more than as the carrier in this article, the discovered anti-aging treatment mechanism Parkinson's disease is not confined to Buyang Huanwu decoction, could also be used to understand the anti-aging treatment mechanism using other prescription. The main contribution of this paper is to clarify the mechanism of anti-aging treatment of Parkinson's disease, and provide a new strategy for the treatment and prevention of Parkinson's disease.

Keywords: Buyang Huanwu decoction; Parkinson′s disease; anti-aging treatment; mechanism research.

MeSH terms

  • Aging / drug effects*
  • Apoptosis
  • Drugs, Chinese Herbal / therapeutic use*
  • Humans
  • Medicine, Chinese Traditional
  • Oxidative Stress
  • Parkinson Disease / drug therapy*

Substances

  • Drugs, Chinese Herbal
  • buyang huanwu