Initial evaluation of a ^99mTc-cyclopentadienyltricarbonyl technetium complex as a potential 5-HT_1A receptor imaging agent

Appl Radiat Isot. 2017 Nov:129:196-203. doi: 10.1016/j.apradiso.2017.08.029. Epub 2017 Aug 31.

Authors

Nadia Malek Saied¹, Najoua Mejri², Mouna Raddaoui¹, Mouldi Saidi¹

Affiliations

¹ Unit of Medical, Agricultural and Environmental Techniques Nuclear Applications (CNSTN), Tuinisia.
² Unit of Medical, Agricultural and Environmental Techniques Nuclear Applications (CNSTN), Tuinisia. Electronic address: najoua.mejri@gmail.com.

PMID: 28886422
DOI: 10.1016/j.apradiso.2017.08.029

No abstract available

MeSH terms

Animals
Autoradiography
Brain / diagnostic imaging
Brain / metabolism
Hippocampus / diagnostic imaging
Hippocampus / metabolism
Humans
Liver / metabolism
Male
Organotechnetium Compounds / chemical synthesis
Organotechnetium Compounds / chemistry
Organotechnetium Compounds / pharmacokinetics*
Protein Binding
Radiopharmaceuticals / chemical synthesis
Radiopharmaceuticals / chemistry
Radiopharmaceuticals / pharmacokinetics*
Rats
Rats, Wistar
Receptor, Serotonin, 5-HT1A / metabolism*
Tissue Distribution
Tomography, Emission-Computed, Single-Photon

Substances

Organotechnetium Compounds
Radiopharmaceuticals
cyclopentadienyl tricarbonyl technetium
Receptor, Serotonin, 5-HT1A