Male Infertility Associated with a Supernumerary Marker Chromosome

Seung Hun Song; Sang Hee Park; Eunah Shin; Jae Hung Jung; Sung Han Shim; Dong Suk Kim

doi:10.5534/wjmh.17015

Male Infertility Associated with a Supernumerary Marker Chromosome

World J Mens Health. 2017 Dec;35(3):205-208. doi: 10.5534/wjmh.17015. Epub 2017 Sep 6.

Authors

Seung Hun Song^{1

2}, Sang Hee Park^{3

2}, Eunah Shin⁴, Jae Hung Jung⁵, Sung Han Shim^{3

2}, Dong Suk Kim^{1

6}

Affiliations

¹ Department of Urology, CHA Gangnam Medical Center, CHA University, Seoul, Korea.
² Fertility Center, CHA Gangnam Medical Center, CHA University, Seoul, Korea.
³ Department of Genetics, CHA Gangnam Medical Center, CHA University, Seoul, Korea.
⁴ Department of Pathology, CHA Gangnam Medical Center, CHA University, Seoul, Korea.
⁵ Department of Urology, Yonsei University, Wonju College of Medicine, Wonju, Korea.
⁶ Fertility Center, CHA Gangnam Medical Center, CHA University, Seoul, Korea. dskim100@chamc.co.kr.

Abstract

A marker chromosome (mar) is a structurally abnormal chromosome in which no part can be identified. The significance of a marker varies, depending on the material contained within the marker. Very few reports have been published of marker chromosomes associated with male infertility. Here, we report the case of an infertile man with a rare variant of a marker chromosome of a mos 47,XY,+mar[25]/46,XY[25] karyotype.

Keywords: Azoospermia; Chromosome aberrations; Infertility, male.

Publication types

Case Reports