A retrospective clinicopathological study of lung adenocarcinoma: Total tumor size can predict subtypes and lymph node involvement

Abstract

Purpose: To analyze the predictive ability of total tumor size in lung adenocarcinoma subtype and lymph node involvement.

Materials and methods: 1018 patients, ≤3cm tumor, were enrolled. The maximum diameter and other variables of each tumor were measured.

Results: The optimal cut-off value for total tumor size in differentiating AIS and MIA from IAC was <1.15cm, in distinguishing lymph node involvement, it was 1.65cm.

Conclusions: Total tumor size could be a reliable predictor of lung adenocarcinoma subtype and lymph node involvement irrespective of ground glass, part solid and solid characteristics.

Keywords: Adenocarcinoma in situ; Invasive adenocarcinoma; Lymph node involvement; Minimally invasive adenocarcinoma; Total tumor size.