Pseudophakic retinal detachment in young-aged patients

PLoS One. 2017 Aug 31;12(8):e0184187. doi: 10.1371/journal.pone.0184187. eCollection 2017.

Abstract

Objective: To investigate the incidence and risk factors for retinal detachment (RD) after cataract surgery or refractive lens exchange (RLE) in patients aged below 61 years.

Methods: Retrospective medical chart review of 7,886 patients (13,925 eyes) who underwent cataract surgery or RLE. Patients aged below 61 years were selected. Age, gender, axial length, follow-up times, and the occurrence of RD were recorded. Additional characteristics documented for RD cases were: history of RD, preexisting retinal findings, laser capsulotomy, status of macula at RD, date and details of RD.

Results: From a total of 421 patients (677 eyes) aged below 61 years 24 cases of RD were identified, resulting in an overall cumulative incidence per eyes of 3.55%. The mean follow-up time was 45 ± 32.8 months. Ninety-two % of all RDs occurred within 3.6 years from surgery. Axial length had a significant effect on the risk of RD after cataract/ RLE surgery (HR = 1.42, P = 0.0001, 95% CI 1.19-1.69). The highest incidence of RD occurred in the subgroup of 25 to 28.9 mm axial length (10.2%). With an increase in age of ten years, the hazard of postoperative RD was not significantly increased by a factor of 1.50 (P = 0.286, 95% CI 0.71-3.15). The highest incidence of RD occurred in patients aged 50-54 years (5.39%). Compared to females, males had an almost twofold not significant risk of postoperative RD (HR = 1.96, P = 0.123, 95% CI 0.83-4.63). None of the RD cases had a history of RD.

Conclusions: Axial length is a significant risk factor for pseudophakic RD. The need for cataract surgery or RLE should be carefully considered in patients with axial lengths between 25 and 29 mm, aged 50-54 years, in males, and in case of preexisting retinal findings.

MeSH terms

  • Adult
  • Cataract Extraction / adverse effects*
  • Eye / physiopathology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myopia / physiopathology
  • Ophthalmologic Surgical Procedures / adverse effects*
  • Postoperative Complications / physiopathology
  • Pseudophakia / etiology
  • Pseudophakia / physiopathology*
  • Retinal Detachment / etiology
  • Retinal Detachment / physiopathology*
  • Risk Factors
  • Young Adult

Grants and funding

The authors received no support or funding for this work.