SNARE proteins in membrane trafficking

Traffic. 2017 Dec;18(12):767-775. doi: 10.1111/tra.12524. Epub 2017 Oct 10.

Abstract

SNAREs are the core machinery mediating membrane fusion. In this review, we provide an update on the recent progress on SNAREs regulating membrane fusion events, especially the more detailed fusion processes dissected by well-developed biophysical methods and in vitro single molecule analysis approaches. We also briefly summarize the relevant research from Chinese laboratories and highlight the significant contributions on our understanding of SNARE-mediated membrane trafficking from scientists in China.

Keywords: SNARE; membrane fusion; membrane trafficking; tethering factor.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Membrane / metabolism*
  • Cell Movement / physiology
  • Humans
  • Membrane Fusion / physiology*
  • Protein Transport / physiology*
  • SNARE Proteins / metabolism*
  • Vesicular Transport Proteins / metabolism*

Substances

  • SNARE Proteins
  • Vesicular Transport Proteins