Effects of Chronic Exposure to Ultrasound of Alternating Frequencies on the Levels of Aggression and Anxiety in CBA and BALB/c mice

Bull Exp Biol Med. 2017 Aug;163(4):409-411. doi: 10.1007/s10517-017-3815-x. Epub 2017 Aug 29.

Abstract

Stress-induced changes in the behavior of CBA and BALB/c mice were studied after 3-week ultrasound exposure (22-45 kHz). The mice of both lines demonstrated increased aggression in the resident-intruder and social interest paradigms and reduced number of social interactions in the social interest test. Elevated plus maze test showed a decrease in anxiety level in CBA mice and an increase in this parameter in BALB/c mice. Chronic exposure to ultrasound induced an increase in aggression level in mice of both lines that was not directly related to changes in anxiety level.

Keywords: aggression; anxiety; mice; stress; ultrasound.

MeSH terms

  • Aggression / radiation effects*
  • Animals
  • Anxiety / therapy*
  • Male
  • Maze Learning / radiation effects*
  • Mice
  • Mice, Inbred BALB C
  • Mice, Inbred CBA
  • Randomized Controlled Trials as Topic
  • Ultrasonic Waves*