Left ventricular assist device: exercise capacity evolution and rehabilitation added value

Acta Cardiol. 2018 Jun;73(3):248-255. doi: 10.1080/00015385.2017.1368947. Epub 2017 Aug 28.

Abstract

Background: With more than 15,000 implanted patients worldwide and a survival rate of 80% at 1-year and 59% at 5-years, left ventricular assist device (LVAD) implantation has become an interesting strategy in the management of heart failure patients who are resistant to other kinds of treatment. There are limited data in the literature on the change over time of exercise capacity in LVAD patients, as well as limited knowledge about the beneficial effects that rehabilitation might have on these patients. Therefore, the aim of our study was to evaluate the evolution of exercise capacity on a cohort of patients implanted with the same device (HeartWare©) and to analyse the potential impact of rehabilitation.

Methods: Sixty-two patients implanted with a LVAD between June 2011 and June 2015 were screened. Exercise capacity was evaluated by cardiopulmonary exercise testing at 6 weeks, 6 and 12 months after implantation.

Results: We have observed significant differences in the exercise capacity and evolution between the trained and non-trained patients. Some of the trained patients nearly normalised their exercise capacity at the end of the rehabilitation programme.

Conclusions: Exercise capacity of patient implanted with a HeartWare© LVAD increased in the early period after implantation. Rehabilitation allowed implanted patients to have a significantly better evolution compared to non-rehabilitated patients.

Keywords: Left ventricular assist device; cardiopulmonary exercise testing; exercise; rehabilitation.

MeSH terms

  • Cardiac Rehabilitation / methods*
  • Exercise Test
  • Exercise Therapy / methods*
  • Exercise Tolerance / physiology
  • Female
  • Follow-Up Studies
  • Heart Failure / physiopathology
  • Heart Failure / rehabilitation*
  • Heart-Assist Devices*
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Time Factors