Advances in rapid drug detection technology

Wen-Bo Zou; Li-Hui Yin; Shao-Hong Jin

doi:10.1016/j.jpba.2017.08.016

Advances in rapid drug detection technology

J Pharm Biomed Anal. 2018 Jan 5:147:81-88. doi: 10.1016/j.jpba.2017.08.016. Epub 2017 Aug 15.

Authors

Wen-Bo Zou¹, Li-Hui Yin², Shao-Hong Jin³

Affiliations

¹ National Institutes for Food and Drug Control, China.
² National Institutes for Food and Drug Control, China. Electronic address: yinlihui@nifdc.org.cn.
³ National Institutes for Food and Drug Control, China. Electronic address: jinshh@nifdc.org.cn.

PMID: 28844368
DOI: 10.1016/j.jpba.2017.08.016

Abstract

Spurious/Falsely-labeled/Falsified/Counterfeit (SFFC)drugs have become a major threat to public health, especially in rural areas of developing countries.The goal of this review is to provide an overview of rapid detection technologies for counterfeits recently reported, such as Near Infrared Spectroscopy, Near Infrared Chemical Imaging, Raman Spectroscopy, X-Ray Fluorescence, X-RayPowder Diffraction, Ion Mobility Spectrometry, Ion MobilityMass Spectrometry,Isotope Ratio Mass Spectrometry and visual analytical methods The advantages of each of these detection methods are introduced. Examples of characterization of SFFC drugs using the detection technology mentioned are presented. In addition, new characteristics and trends of SFFC drugs are listed and the solution is discussed.

Keywords: Counterfeits; Rapid detection; SFFC drug.

Publication types

Review

MeSH terms

Counterfeit Drugs / analysis*
Developing Countries
Limit of Detection
Powder Diffraction
Spectrum Analysis / methods*

Substances

Counterfeit Drugs