Insight into the deprotonation at the half-equivalence point of (thio)amido-benzimidazoles in the presence of anions

S Koeller; M-H Lescure; C Davies; J-P Desvergne; S Massip; B Bibal

doi:10.1039/c7ob01704a

Insight into the deprotonation at the half-equivalence point of (thio)amido-benzimidazoles in the presence of anions

Org Biomol Chem. 2017 Sep 13;15(35):7263-7266. doi: 10.1039/c7ob01704a.

Authors

S Koeller¹, M-H Lescure, C Davies, J-P Desvergne, S Massip, B Bibal

Affiliation

¹ Université de Bordeaux, Institut des Sciences Moléculaires UMR 5255, 351 cours de la Libération, 33405 Talence, France. brigitte.bibal@u-bordeaux.fr.

PMID: 28832051
DOI: 10.1039/c7ob01704a

Abstract

Three crystallographic structures highlight the acid-base half-equivalence point of hydrogen-bond donor (thio)amido-benzimidazoles induced by fluoride or benzoate salts with concomitant hydrogen-bonding and deprotonation as a merged synergic process.