Rearrangements of α-Diazo-β-hydroxyketones for the Synthesis of Bicyclo[m.n.1]alkanones

Zhengning Li; Shuk Mei Lam; Ignatius Ip; Wing-Tak Wong; Pauline Chiu

doi:10.1021/acs.orglett.7b01963

Rearrangements of α-Diazo-β-hydroxyketones for the Synthesis of Bicyclo[m.n.1]alkanones

Org Lett. 2017 Sep 1;19(17):4464-4467. doi: 10.1021/acs.orglett.7b01963. Epub 2017 Aug 22.

Authors

Zhengning Li¹, Shuk Mei Lam¹, Ignatius Ip¹, Wing-Tak Wong¹, Pauline Chiu¹

Affiliation

¹ Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong , Pokfulam Road, Hong Kong, P. R. China.

PMID: 28829145
DOI: 10.1021/acs.orglett.7b01963

Abstract

Rhodium-catalyzed decomposition of fused bicyclic α-diazo-β-hydroxyketones results in good yields of bridged bicyclo[m.n.1]ketones via a rearrangement pathway.

Publication types

Research Support, Non-U.S. Gov't