Objectives: 1) To analyze screening performance of second trimester scan for ACC, 2) to evaluate the agreement between ultrasound and MRI and 3) to compare prenatal and postnatal diagnosis.
Methods: It was a prospective observational study. All patients with fetuses suspected of ACC were referred to prenatal MRI (pMRI).
Results: One subject was not confirmed by pMRI with the diagnosis of ACC. This case demonstrated partial ACC in neonatal MRI (nMRI).
Conclusion: Sensitivity of second trimester scan for callosal agenesis of 73% and specificity of 99%. Prenatal MRI and US has similar amount of misdiagnoses.
Keywords: Agenesis; Callosal; Prenatal magnetic resonance imaging; Screening; Ultrasound.
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